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Nicotine and Nicotinic Receptors: Pharmacology Discussion Post

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SCENARIO 4

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When a person uses nicotine, it causes temporary feelings of relaxation and well-being. Nicotine binds to nicotinic receptors in the brain, augmenting the release of numerous neurotransmitters. Name at least three of these neurotransmitters. Patients may self-medicate ADHD, anxiety, and depression by smoking. Is there a medication that could treat ADHD, anxiety, depression, and provide smoking cessation? Write a complete medication order for this medication. Does the patient need to quit smoking before starting treatment?

SCENARIO 4

Nicotine acts upon nicotinic receptors in the brain, thereby causing the discharge of dopamine, norepinephrine, and serotonin. This mechanism can help justify why people provide nicotine to treat diseases like ADHD, anxiety, and depression, among others. These conditions and smoking cessation can be treated with the help of bupropion, which is sold under the name of Wellbutrin SR (Zhang et al., 2023).

A complete prescription for this purpose would be as follows, Bupropion sustained release of 150mg in the pack of 60 tablets. One tablet should be taken orally for the first three days, while one tablet should be taken two times daily for smoking relief, ADHD, and depression and with a single refill (Naguy & Badr, 2022).

There is no requirement for the patient to stop smoking before they begin the program and take bupropion. In most cases, the second party wishes to quit dates before the two weeks the medication is administered. Supervision during treatment is quite an elaborate process and entails the following. The status of the phenomenon of interest, such as the patient’s mood, anxiety levels, and whether they are smoking, should be assessed frequently (Picciotto & Kenny, 2021). One also has to consider the side effects; for example, one may develop insomnia or agitated feelings during treatment. Also, compliance with the suggested regimen and the drug’s effectiveness should be revisited after 4-6 weeks if the best results are required.

References

Naguy, A., & Badr, B. H. (2022). Bupropion—myth-busting!. CNS spectrums , 27 (5), 545-546.

Picciotto, M. R., & Kenny, P. J. (2021). Mechanisms of nicotine addiction. Cold Spring Harbor perspectives in medicine , 11 (5), a039610.

Zhang, H., Gilbert, E., Hussain, S., Veldhuizen, S., Le Foll, B., Selby, P., & Zawertailo, L. (2023). Effectiveness of bupropion and varenicline for smokers with baseline depressive symptoms. Nicotine and Tobacco Research , 25 (5), 937-944. When a person uses nicotine, it causes temporary feelings of relaxation and well-being. Nicotine binds to nicotinic receptors in the brain, augmenting the release of numerous neurotransmitters.

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